Viagra Alternative: How Kisspeptin Injections Increase Sexual Desire
Kisspeptin is a protein encoded by a DNA strand of the KISS1 gene. This hormone was discovered in 1996, and scientists knew it played a role in sperm and egg production. However, these were not considered to be of significant importance to the functioning of the human body until 12 years later, when researchers from Imperial College London conducted a new study published in the medical journal JCI Insight. They discovered that this biologically active substance is involved in the regulation of sexual behavior and influences male sexual desire. Article Contents:
Chocolate, Kisses, and Genetics
Experiment on Men
The Hershey Company, the largest confectionery company in the world, is also located in Hershey, Pennsylvania. The Hershey Company produces Hershey”s Kisses, the famous brand of chocolate candies that have become the manufacturer”s signature. The old factory building was nicknamed “The House of Hershin Kisses” after the confectionery factory, and the gene code Kiss1 was given its name in its honor.
Experiment on Men
Test Results
To study how kisspeptin acts in different parts of the brain, scientists from Imperial College London conducted a two-stage experiment involving 29 men. The subjects were placed in MRI scanners, allowing the researchers to continuously monitor brain activity. In one study, the men were administered hormones intravenously, while in the other, they were unaware of the nature of the treatment, such as a placebo injection.
After the injection, the men were shown images of a sexual nature, negative (a car accident or a face distorted by fear) and neutral (cups, other objects, a calm image of a face). After the scan, the men filled out a questionnaire regardless of whether they took hormones or a placebo.
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The researchers monitored the participants” brain activity while they viewed the images. And when they didn’t see them, i. e. when their brain was at rest (passive mode). These two methods allowed the researchers to compare normal brain activity with the response when receiving gelpeptin.
Test results
Opinions of Authorities
Scientists also explained the importance of studying neural networks in the passive mode of the brain, that is, when the brain is not focused on any task. Studying the neutral resting state of the brain is important for understanding what happens when the brain is active. Passive observation allows you to examine more areas of the neural network and see how it is affected by certain hormones or drugs. This provides clues for the treatment of many mental illnesses.
Senior study author Dr. Waldit Dillo, Ph. D., director of the School of Endocrine Medicine at Imperial College, said. Now, for the first time, we have demonstrated the effects of hormones on the brain in a passive surgical manner. These findings indicate that conditions such as low desire for sex and depression can be treated following the use of kisspeptin.”
Opinions of authorities
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The study”s first author, Alexander Komninos PhD, an expert in endocrinology at Imperial College London, said: “Our findings reveal several complex roles for the naturally occurring protein kisspeptin and the control and management of reproductive hormones, as well as emotional and sexual functioning.
Today, almost all people experience low sexual urges, which can be detrimental to their well-being as a couple. While there is still a lot of work to be done, this research is already opening up possibilities for treating similar problems.”
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